Dr. Frederic Zenhausern, a Professor at the Translational Genomics Research Institute (TGen) and developer of a rapid DNA processor, has been named to the Fellows of the National Academy of Inventors (NAI).
Zenhausern, Ph.D., MBA, will be inducted into the NAI Fellows by Deputy U.S. Commissioner for Patents Andy Faile, from the U.S. Patent and Trademark Office, during the 3rd Annual Conference of the National Academy of Inventors, March 7, 2014, in Alexandria, Va. Fellows will be presented with a special trophy and a rosette pin.
Zenhausern also is a Professor and Director of the Center for Applied Nanobioscience and Medicine at the University of Arizona College of Medicine – Phoenix. The center uniquely applies a combination of advances in nanoscience, microelectromechanical systems, molecular biology, and genomics to a new generation of biological tools and sensors based on nano and microscale technologies.
Applying interdisciplinary science approaches to medicine, Zenhausern’s work is aimed at early diagnostics of human diseases, in particular, integrating bioassay chemistries with several biomarkers and targets developed by researchers at TGen.. Over the years, his team has collaborated on multiple projects at TGen for designing bioanalytical platform technologies to translate molecular analysis into clinical tools and, ultimately, promoting adoption of novel technologies for point-of-care diagnostics applications.
The Microfluidic DNA Analysis System (MiDAS), a desktop printer-sized box that is described as robust and user-friendly, is one of Zenhausern’s innovations. The integrated DNA analyzer can be transported directly to a point-of-care or deployed in a mobile setting, eliminating some of the issues that arise when collecting and shipping a specimen from a remote site to a centralized laboratory for molecular testing. The core technology is also enabling the rapid automation of preparation of a biological sample for interfacing with various high-resolution analytical instrumentations, such as Next Generation Sequencing. These emerging diagnostic tools in personalized medicine are being used the team of clinicians at TGen Clinical Translational Research Division.
A similar platform was configured for genomic assays ready for implementations in medical countermeasures against radiological and nuclear disasters, and also applicable in clinical settings for predicting which patients are most sensitive to radiation in guiding personalized treatment, and preventing the development of toxicities that may result from radiotherapy. These innovations are described in multiple patents with TGen co-inventors, which led to significant federal funding of Arizona academic institutions, and to generating commercial interest and licensing from multiple U.S. companies, also contributing to Arizona’s economic development.
Zenhausern has co-authored more than 70 scientific publications and is named on many pending and more than a dozen issued U.S. patents in various domains ranging from DNA sequencing to optical data storage. Zenhausern’s responsibilities also include leading clinical research at the personalized medicine research laboratory at Scottsdale Healthcare Research Institute and serving on several corporate scientific boards and international consortia in life sciences.
Election to NAI Fellow status is a high professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.
The 143 innovators elected to NAI Fellow status represent 94 universities and governmental and non-profit research institutes. Together, they hold more than 5,600 U.S. patents.
Included in the 2013 class are 26 presidents and senior leadership of research universities and non-profit research institutes, 69 members of the National Academies, five inductees of the National Inventors Hall of Fame, six recipients of the U.S. National Medal of Technology and Innovation, and nine Nobel Laureates among other major awards and distinctions.
Academic inventors and innovators elected to the rank of NAI Fellow were nominated by their peers for outstanding contributions to innovation in areas such as patents and licensing, innovative discovery and technology, significant impact on society, and support and enhancement of innovation.