Tag Archives: christine jones

bioscience

Arizona bioscience industry producing ‘aha’ moments

AZBio Expo 2014 had “aha moments” at every turn. With over 250 entrepreneurs, innovators, business leaders, legislators, scientists and researchers in attendance, the energy was sizzling and the outlook endless. Here are just a few of the event highlights, appropriately, A to Z:

A – Access to Capital is the key. No money. No honey. Capital fuels innovation and commercialization. In the first panel discussion of the day – Funding Paths for Innovators – AZBio chief Joan Koerber-Walker engaged Mary Ann Guerra (BioAccel), Paul Jackson (Integrus Capital/Worthworm) and Kelly Slone (National Venture Capital Association) in a no-holds barred discussion. “The entire ecosystem has changed,” according to Slone. “After the tech bubble burst, available venture dollars have been virtually cut in half.” Guerra explains that only one in 100 will get angel funding – and then only one in 100 will get venture funding. We need to think of new ways to help our startup entrepreneurs get funding.” Jackson urges innovators to think like investors and offers one solution with his online valuation process, Worthworm.

B – Bridging the Gap with the 21st Century Cures Initiative. “No industry has to face the challenges we face to bring a product to market,” says Koerber-Walker. “We have new hope in the 21st Century Cures Initiative. Google it. Watch the videos, See what they are doing. There is exciting stuff happening and some of it is happening in Arizona.”

C — Cure Corridor. Scottsdale’s Mayor Jim Lane shares his pride and plans for the largest concentration of bioscience businesses in the U.S., the Cure Corridor, bounded on one side by the Scottsdale Airpark on the West, and the Fountain Hills Mayo facility on the East, “a major driver of our economy, with $2½ billion in direct economic impact and $3.5 billion in indirect impact.” According to Lane, “Health and wellness are a part of Scottsdale’s identity. We should never stop asking how we can find new answers alleviate pain, restore health and improve the quality of life.”

D – Discovery. Development. Delivery. Valley Fever Solutions CEO David Larwood shared his company’s formula for achieving success in development and funding – The Five R’s:

Right drug.
Right patient.
Right safety.
Right time. (How long before we can sell it?)
Right reimbursent.

E – Epigenetics and Personalized Medicine. Start-up company INanoBio founder and CEO Bharath Takupalli, explained that the genome sequencing market is expected to grow to $10 billion by 2020. With a unique capability to combine nanotechnology and biomedicine, his company is in the lead for building new solutions now. “We aim to develop a $100 ultrafast nanopore-based desktop sequencer – a point-of-care diagnostic” that will help change the face of healthcare, he explains.

F – Funding needs to be the focus for the future. According to a Flinn Foundation/Batelle report, “Arizona has many bioscience strengths and opportunities, but a substantial increase in private and public investment will be needed over the next decade to realize the [Flinn Foundation’s] Roadmap’s goals.” Last year, Arizona bioscience sector attracted $37 million in venture capital investment, up from $23 million from 2012, but that is only a fraction of the $9.8 billion invested nationally.

The goal is to increase the annual investment up to $40 million for seed capital in emerging companies and up to $125 million in venture capital.

G – Genomic advances hold high hopes for positively disruption. Explaining that healthcare premiums are growing at three times the rate of inflation and wages, Frederic Zenhausern, Ph.D., MBA, president of Whitespace Enterprise, says “The new era of precision healthcare (also called personalized healthcare) will provide more accessibility, transparency and health information to improve – dramatically – quality and lower cost over time.” His start-up company, based in Fountain Hills, develops methods for automating and miniaturizing the workflow processing of biological specimens.

H – Henry Ford.“I am looking for a lot of men who have an infinite capacity to not know what can’t be done,” said Henry Ford. So does Robert Penny, M.D., Ph.D., co-founder and CEO of the International Genomics Consortium and founder and CEO of Paradigm. “Phoenix has become the Grand Central Station for all the aggregating and analyzing cancer tissues. We have 10,000 tumors – and the information is publicly available. This will accelerate cancer discovery at a rate faster than ever,” he says. “This is a tidal wave that Arizona has led. Everyone in this room should be grabbing a surfboard and figuring out how to ride it.”

I – IPO: The nation’s top IPO of 2013 is right here in Chandler. With 380 percent growth in shareholder value, Insys Therapeutics, a commercial-stage specialty pharmaceutical company, ended the year with a market cap of $800 million. Darryl Baker, the chief financial officer, explained how the company, founded in 2002 by Dr. John Kapoor, was determined to discover better ways to deliver existing medications to patients. A sublingual fentanyl spray technology delivers treatments to opioid-tolerant cancer patients and holds real possibilities for better helping patients with acute pain, major burns and pediatric issues. In the R&D pipeline now is the development of a pharmaceutical cannabinoid, aimed at easing epilepsy, peripheral neuropathy and cocaine addiction.

J – Jobs: 107,000 bioscience jobs – good-paying and growing. Arizona has nearly 107,000 bioscience jobs, based on 2012 industry data, and the sector contributes an estimated $36 billion in revenue to the state’s economy, according to a study by the Ohio-based Battelle Technology Partnership Practice. Hospitals account for 83,000 of those jobs and $22 billion of the revenue. Arizona’s average annual wage in the bioscience sector is $62,775, 39 percent higher than the private-sector average, the report said. Not counting hospital jobs, the average wage for bioscience jobs jumps to $85,571. (2013 data).

K – Kalos Therapeutics is building a promising platform for future drug discovery. Start-up innovator Michael Kozlowski, OD, Ph.D., chief science officer of Kalos Therapeutics, explains that their focus on transforming the atrial natriuretic family of peptides engages a natural biochemical mechanism. This approach holds promise for people with pancreatic cancer because it results in a more complete response, reduced side effects and improved safety and a longer period of effectiveness.

L – Let’s leverage every resource, strength, collaboration and person we’ve got! Arizona’s bioscience industry is aiming to increase research revenue for institutions statewide by 69 percent over the next decade to $782 million and attract additional anchors for the sector.

M – Medtronic models aggressive, needs-focused growth. Keynote speaker Ron Wilson, vice president and general manager of the Medtronic Tempe campus made it clear that passion for people runs through his veins. Locating a small manufacturing facility here in 1973, the company’s facility today covers 30 acres, has 900 employees and generates $17 billion in revenues. How do they do it? We follow our founder’s vision still: We understand what the unmet needs are and we apply our knowledge for the good of people all over the world.”

N – Next Level. “Arizona has made unprecedented progress over the last decade in developing the talent, building research infrastructure, and growing its base. Taking it to the Next Level will require new collaborative partnerships, forward looking leaders, and aggressive investments from both the public and private private sectors to take our place in the top tiers globally,” shared Koerber-Walker. ”Now is our time. Let’s get it done!”

O – Orphans no more. Valley fever, considered an orphan disease, hits about 150,000 people a year – 60 percent live in central Arizona. Current treatments have major shortcomings, with about 60 percent of those treated being unresponsive. The result is 2,000 serious cases and 150 deaths a year. It affects pets in nearly equal proportion. David Larwood, CEO of Valley Fever Solutions, has some answers. His company is developing Nikkomycin Z (NikZ) as a dramatically superior potential cure for Valley Fever. To help raise awareness and prevention, the Arizona Board of Regents created Valley Fever Corridor project, a public health program led by University of Arizona College of Medicine’s John Galgiani, MD, who is also the chief medical officer for Valley Solutions.

P – Policymakers are on board. Gov. Jan Brewer’s time is coming to a close and it’s time to decide which candidate can bring their best to bioscience. Recognizing that the Arizona bioscience sector is growing at four times the rate of the national average, candidates Christine Jones, Doug Ducey, Fred Duval, Ken Bennett and Scott Smith shared their ideas on how to ramp up funding and revenues in 90-second videos. Koerber-Walker says, “The most important thing we can do this summer is vote in the primaries.”

Q – Cues: Here are a few Q’s for success. Some lessons learned, courtesy of Robert Penny:

Make sure you have:

Complementary skills and expertise
Trust
Interpersonal chemistry (It’s better to navigate bumps in the road with people you trust than people you don’t!)

Pick the right projects:

Big enough to be worthy of your efforts
Complex enough to need partnerships
Audacious enough to move the field

R – Remembering Polio: Can Looking Back Catapult Us Forward? How did we cure the world of polio? What did it take to conquer the most feared disease of the 20th Century? What threatens our world today and how can we continue to keep people healthy with the right vaccines, for the right person at the right time? Gaspar Laca, state government affairs director at GlaxoSmithKime, engaged David Larwood, CEO and president of Valley Fever Solutions (and a person who has been directly affected by polio) and Rep. Debbie McCune Davis, executive director of The Arizona Partnership for Immunization, in a rousing discussion of what’s happening in Arizona today, the mounting threats of the ”vaccine exemptors,” and what we need to do now. (See Vaccines.)

S – Shoes. Did you see those shoes? “Give a girl the right shoes and she can conquer the world!” Enough said.

T – Tucson’s Critical Path Institute creates new tools. A jewel in the bioscience crown – and located right here in Arizona! The Critical Path Institute (C-Path) is a breakthrough organization, creating a new movement: “consensus science.” Keynoter Martha Brumfield. Ph.D, president and CEO, shared what can be achieved when people come together with the belief that a “rising tide floats all boats.” Working to improve the unacceptable 95 percent failure rate in the testing of new drug therapies, C-Path is improving medical product development efficiencies by identifying pathways that integrate new scientific advances into the regulatory review process. Check out their Alzheimer’s clinical trial simulation tool.

U – United we stand. Mayors Jim Lane (City of Scottsdale) and John Lewis (Town of Gilbert) will join Koerber-Walker and an Arizona bioscience-business contingent next week at the 2014 BIO International Convention in San Diego (June 23-26), the world’s largest biotechnology gathering. They will surely scoop up new ideas, new connections – and with any luck, new investment!

V – Vaccines: Get ‘em! Talk about ‘em. Challenge the myths. Explain the realities. Polio. Measles. And whooping cough today. Without proper vaccinations, whooping cough (pertussis) could be the polio of our time. “As science-minded people, the best thing you can do is activate conversations about the importance of vaccinations. Here’s some help: Why immunize?

W – White Hat event brings in national investors. (Apply by July 15th.) “AZBio’s White Hat Investor’s Conference is the first ever life science specific investor conference to be held in Arizona,” says Koerber-Walker. “Kelly Slone [of the National Venture Capital Association] has been an amazing partner to bring this together along with the state bioscience association leaders from across the Rocky Mountain Southwest Region. Investors and investment firms from across the country will be here, so get involved. Even if you feel like you are not ready yet, take the leap and apply to present. “

X – “X” marks the spot for our next big gathering. Wear your White Hat! The West was won by innovators, investors, and prospectors who understood the value of discovery and accepted the challenge of investing in new frontiers. Meet a new generation of biotech and healthcare pioneers at White Hat Investors 2014, the first annual biotech and healthcare investor conference that showcases the best of the Rocky Mountain & Southwest Region.

Bioindustry Associations from across the Rocky Mountain and Southwest Region are coming together to present an opportunity for Angels, Venture Capitalists and Strategic Investors to connect with the best biotech and healthcare investment opportunities from across the Rocky Mountain & Southwest states at White Hat Investors 2014 in Phoenix, Arizona on September 17 & 18, 2014.

Presenting Companies will be selected from the region’s emerging innovator leaders in the fields of:

Diagnostics
Therapeutics
Medical Devices
Health IT

Y – Young Talent is being cultivated. We got it! With nearly 50 abstracts accepted and student presenters presenting at the Expo, Koerber-Walker got it right when she said, “These young people are going to be working on things that we can’t even begin to imagine!” Arizona’s tremendous mentoring people and organizations are sharing knowledge, support and inspiration. For example University of Arizona student Keeley Brown is destined to help the world crack the code on genetically modified foods and farming. (Her presentation was the “Epigenetic Effects of Transgenic Manipulation in Glycine Max (Soybeans).

Zzzzzzzzz – No one fell asleep at this conference! Catherine Leyen, founder and CEO of start-up RadiUp, says she comes to AZBio to stay abreast of the action, connect with like-minded people and soak up inspiration. Her verdict of AZBIO Expo 2014? Mission accomplished!

CHRISTINE JONES HEADSHOT, WEB

Christine Jones Talks to American Subcontractors Association Panel

On Tuesday, the American Subcontractors Association of Arizona hosted a gubernatorial candidate panel to discuss policies vital to economic development and improvement of the business environment for the construction industry. Former Go Daddy Executive Vice President Christine Jones, Secretary of State Ken Bennett, Mesa Mayor Scott Smith and State Senator Al Melvin participated in the panel.

“In order for Arizona to become an economic powerhouse, it is imperative that our next governor understand the nexus of business and policy,” Jones said. “Today’s panel offered very distinct visions for the future of our state and I was honored to share my background as a policy maker and business leader to outline my plans to grow our local economies, create jobs, and stand up to the federal government on issues such as overregulation. I would like to thank the American Subcontractors Association for hosting today’s substantive discussion on economic development, an issue of critical importance to Arizona’s future.”

ACC Awards 2012

ACC Awards 2012 Finalists: H-M

Effective corporate counsel has never been more important than it is now. Arizona Business Magazine is recognizing the important and vital role that in-house counsel plays in the success of a business with the Arizona Corporate Counsel Awards, ACC Awards 2012. The 27 finalists and winners were honored Thursday, January 12 during a ceremony and dinner at the Ritz Carlton Phoenix. Here are the finalists in alphabetical order, H through M.


ACC Awards 2012 Finalists, H through M:

George Hittner
Corporate secretary, general counsel, vice president of governmental relations
American Traffic Solutions

ACC Awards 2012Hittner has overseen more than 150 lawsuits for ATS throughout the country, ranging from minor cases to multi-million-dollar class actions, with a 98 percent win rate since October 2008. Some highlights:
* Under Hittner’s leadership, ATS has never lost a constitutional challenge to one of its programs.
* Hittner led the successful legal strategy which resulted in a decision by the 6th Circuit U.S. Court of Appeals that found the Akron, Ohio, intersection and speed camera safety ordinance legal and constitutional.
* Hittner’s focus on election law has protected the photo enforcement industry from illegal elections, including having three illegal elections declared invalid.


Christine Jones
Executive vice president, general counsel and corporate secretary
Go Daddy Group

ACC Awards 2012Jones is the leader for all legal affairs at Go Daddy. Go Daddy’s legal department is unique in that it encompasses functions that are not traditionally seen in corporate legal departments. Jones supervises more than 100 people in the legal, domain services, network abuse, and government relations departments. Jones has become and industry leader and activist in addressing Internet abuse, and she created the government relations department at Go Daddy to establish a respected presence and voice in Washington. To keep up to date, Jones enables legal professionals to present in-house continuing legal education programs on a monthly basis.


Sara Lee Keller
Executive vice president and general counsel
Clear Channel Outdoor, Inc. — Americas

ACC Awards 2012Since Keller was hired on Jan. 4, 2011, she has grown the legal department from four attorneys to seven. Issues that were traditionally handled by outside counsel are now handled in-house, resulting is cost savings and better management of external spending. Some opinions of her work:
* “Our legal team at Clear Channel Outdoor is becoming a full-service firm right inside the four walls of the company,” said Joe Bagan, Clear Channel’s COO.
*  “This collaboration has improved our overall effectiveness as measured by successful outcomes, more closely managed costs … greater business impact, and improved client satisfaction,” said Ron Cooper, CEO of Clear Channel.


Christopher Kevane
Senior vice president and general counsel
Rural/Metro Corporation

ACC Awards 2012Kevane has been advising and managing the legal affairs for Rural/Metro for more than seven years, the past two as senior vice president and general counsel. His recent accomplishments include managing all legal matters related to:
* The successful close of Rural/Metro’s acquisition by affiliates of the global private equity firm Warburg Pincus LLC.
* The successful acquisition of multiple competitor companies throughout the nation.
* Regulatory matters related to SEC reporting mandates.
* Legal issues and settlement negotiations related to federal and state Medicare and Medicaid audits and compliance matters.
* Contract matters and negotiations surrounding executive departures and hiring.


Mark Larson
Vice president and chief litigation counsel — aerospace and transportation systems
Honeywell International

ACC Awards 2012Given Honeywell Aerospace’s content on global aircraft, chances are that if an aircraft accident occurs, Honeywell will be involved in litigation and Larson will ultimately become involved. Larson oversees a large, complex and diversified docket, encompassing litigation and arbitration matters throughout the world. Through skillful negotiation, Larson managed to settle a number of significant claims last year alone, saving Honeywell hundreds of millions of dollars, as well as protecting Honeywell’s product reputation and brand. In his 11 years at Honeywell, Larson has had just one trial loss. He accomplished all that while reducing outside counsel spending by almost 50 percent since 2007.


Ryan Liebengood
Intellectual property attorney
ASM America INC

ACC Awards 2012Colleagues admire Libengood for his unselfish community service. “I have been in the legal field for more than 40 years and as an in-house attorney for more than 15 years,” said Gary A. Smith, general counsel for Phoenix Engineering Services in Mesa. “Rarely have I seen a relative newcomer to the law become so enthusiastically involved in the community.” Libengood became a member of the Mesa Family YMCA, offering his assistance as the organization transitioned from a fitness facility to a service organization supporting a low-income population. He also volunteers with the Mesa United Way Volunteer Income Tax Preparation Program.


Virginia Llewellyn
General counsel and corporate secretary
Barrett-Jackson Auction Co., LLC

ACC Awards 2012Llewellyn has been general counsel at Barrett-Jackson since 2005. In this role, she is responsible for managing all the company’s legal affairs and overseeing outside counsel relationships. She serves as corporate secretary and works closely with other members of the senior management team on establishing and implementing company policies and procedures as they apply to employees, customers, and external business partners. She also serves as the primary liaison to the company’s media partners, including Fox’s SPEED Channel, which broadcasts more than 100 live hours of Barrett-Jackson events each year to more than 80 million homes.


Matthew D. Mitchell
Vice president legal, associate general counsel
Apollo Group

ACC Awards 2012Mitchell’s original responsibilities for Apollo — one of the largest employers in Arizona — were limited to the employment area, but he has since taken on litigation and regulatory responsibilities. Some highlights:
* He has been instrumental in implementing standard processes for the engagement of outside counsel (including outside counsel guidelines and electronic billing), e-discovery and litigation holds, Apollo board litigation updates specific to both the company and the for-profit education industry, and litigation tracking.
* Has assumed responsibility for securities litigation, derivative actions, wage hour class actions, qui tam litigation, and consumer litigation.


Harriet Mountcastle-Walsh
Vice president and general counsel
Honeywell International

ACC Awards 2012Since assuming the role of aerospace general counsel in 2005, Mountcastle-Walsh has forged a successful vision for the Honeywell Aerospace, Law, Contracts and Export (LC&E) function. Some highlights:
* Developed policies, procedures and best practices to streamline functionalization and reduce total expenses by more than 35 percent.
* Consistently strives to upgrade talent in her 400-person department through hiring efforts, and through a training, mentoring and a development process.
* Enabled growth at Honeywell through the development of its patent portfolio and IP licensing.
* Proactive litigation management has helped reduce Honeywell’s spending on outside counsel by more than 50 percent.


Arizona Business Magazine January/February 2012