Tag Archives: gbm

Dr. Nader Sanai, Barrow Neurological Institute

Ivy Foundation grants $885K to Barrow

The Ben & Catherine Ivy Foundation  has awarded an $885,294 grant to Barrow Neurological Institute for brain cancer research.

The Ivy Foundation is the largest privately funded brain cancer research foundation in North America. Catherine Ivy is the founder and president of the Ivy Foundation, which has a research funding focus on glioblastoma multiforme (GBM), the most common and deadliest of malignant primary brain tumors in adults.

The Barrow brain cancer research program is summarized by the following:

  • In glioblastoma, cancer stem cells are thought to be the driving force of tumor progression and recurrence.
  • The research team has identified a reservoir of cancer stem cells in humans that is undetectable by conventional MRI.
  • This study is the world’s first brain tumor clinical trial targeting cancer stem cells with focused radiotherapy beams.
  • With this strategy, the team hopes to eliminate a source of glioblastoma recurrence, as well as cut off its outlet for its spread to other brain regions.
  • The hope is to turn glioblastoma from a multi-focal disease to a self-contained process that can be controlled with localized therapy.

“With support from the Ben & Catherine Ivy Foundation, we can now finally take the steps necessary to develop and test this strategy in newly-diagnosed glioblastoma patients,” says Nader Sanai, MD, director of the Barrow Brain Tumor Research Center. “Our hope is that it will not only be a relatively safe strategy, but one that starkly impacts the ability of glioblastomas to recur or move beyond its site of origin in newly-diagnosed patients.”

The progress only continues.

“We are encouraged and remain strongly committed to moving the progress forward for patients diagnosed with brain cancer,” said Ivy. “Barrow Neurological Institute is an important strategic partner in our objective to double the life expectancy of people diagnosed with GBM within the next seven years.”

prevention trial - brain scan images

Ivy Foundation Grants Over $9M for Brain Cancer Research

The Ben & Catherine Ivy Foundation (Ivy Foundation) announced its 2012 grant recipients, which total more than $9 million in funding for brain cancer research. The Ivy Foundation is the largest privately funded brain cancer research foundation in North America. Catherine Ivy is the founder and president of the Ivy Foundation, which has a research funding focus on glioblastoma multiforme (GBM), the most common and deadliest of malignant primary brain tumors in adults.

The Ivy Foundation awarded the following grants and/or provided funding in 2012:

· $2,500,000 over three years:  Principal Investigator, Greg D. Foltz, M.D., Director, The Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Medical Center
· $5,000,000 over five years:  Principal Investigators, John Carpten, Ph.D. and David Craig, Ph.D., Translational Genomics Research Institute (TGen) – a collaborative effort with University of California, San Francisco; University of California, Los Angeles; Memorial Sloan-Kettering Cancer Center; Massachusetts General Hospital; Dana Farber/Harvard Cancer Center; MD Anderson; and University of Utah
· $45,000 annually: Principal Investigator, Brandy Wells, Translational Genomics Research Institute (TGen), for the Ivy Neurological Sciences Internship program
· Over $2 million paid out in 2012 for previously committed multi-year brain cancer research grants

“We are encouraged and remain strongly committed to moving the progress forward for patients diagnosed with brain cancer,” said Ivy. “The 2012 Ivy Foundation grant recipients are important strategic partners in our objective to double the life expectancy of people diagnosed with GBM within the next seven years.”

brain cancer

Nation’s Largest Brain Cancer Foundation Moves To Scottsdale

The largest privately funded national foundation focusing solely on brain cancer research has moved from the San Francisco Bay area (Palo Alto, Calif.) to Scottsdale. The Ben and Catherine Ivy Foundation is dedicated to funding research that improves the survival and quality of life for people with brain cancer, which are known as gliomas. Since 2005, it has contributed more than $50 million to brain cancer research in the United States and Canada, with much more funding planned.

“There is a cluster of excellent research institutions located in Phoenix, such as TGen, Barrow Neurological Institute and St. Joseph’s Hospital, with growing potential to make critical strides in brain cancer research,” said Founder and Board President Catherine Ivy, of the Ben and Catherine Ivy Foundation. “Funding these institutions and encouraging collaborations will enhance the funding we have done previously and move us closer to our goal: Doubling the survival rate of people diagnosed with gliomas within seven years from now.”

The Ben and Catherine Ivy Foundation was created in 2005 after Ben Ivy was diagnosed with a glioblastoma (GBM) and passed away four months later. A broad variety of tumors can form in the brain causing evident symptoms and approximately 40 percent of these will be diagnosed as GBM, the most aggressive form of brain cancer. Several well-known people have lost their lives due to GBM, including Senator Ted Kennedy in 2009 and Wall Street billionaire and CEO of IMG Worldwide Ted Forstmann in 2011.

Catherine Ivy is a native of Phoenix, where she grew up before moving to Palo Alto, Calif., for several years.

For more information on the Ben and Catherine Ivy Foundation, visit the Ivy Foundation’s website at ivyfoundation.org.