Tag Archives: Oro Valley

405 W. Cool Dr, CBRE

ACTUS Biotechnology Leases Office in Oro Valley

CBRE has completed a 1,793-square-foot office lease at 405 W. Cool Dr. in Oro Valley, Ariz. The tenant, technology development company ACTUS Biotechnology, relocates from its current space in Oro Valley in anticipation of growth.

Jeff Casper and David Montijo with CBRE’s Tucson office represented the landlord, Tucson-based Louey Holdings LLC, in negotiating the lease terms. ACTUS, also of Tucson, was represented by Bob Davis and Tom Hunt with Rein & Grossoehme Commercial Real Estate’s Tucson office.

Technology companies continue to be amongst the most active sectors in the Tucson office market,” said CBRE’s Casper. “The growth and success of companies like ACTUS will be essential to help create sustainable momentum in the market.”

Built in 2002, the property is located just north and west of Oracle and Magee Roads. Featuring proximity to amenities and abundant at-door parking, the 10-unit office condo is now 70 percent leased.

medical.research

BIO5-TGen collaboration targets Alzheimer’s disease

BIO5 Oro Valley today announced a collaboration with the Translational Genomics Research Institute (TGen) to develop new therapies for the treatment of Alzheimer’s and other neurodegenerative diseases.

BIO5 Oro Valley co-Director and University of Arizona College of Pharmacy medicinal chemist Dr. Christopher Hulme’s collaborative effort with TGen Assistant Professor Dr. Travis Dunckley will focus on the development of novel, small molecule inhibitors of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Upregulation of this kinase is implicated in promoting memory deficits associated with Down syndrome and neurodegenerative pathologies, particularly Alzheimer’s disease.

“DYRK1A is a well-validated, recently discovered target, ready for translational efforts to deliver an oral medication to patients suffering from this insidious disease,” said Dr. Hulme. “Indeed, coupled with the advanced small molecules in-hand that target DYRK1A, further efforts are underway that will broaden our therapeutic presence in the Alzheimer’s arena to other Arizona-based biological discoveries.”

Statistics from the National Institutes of Health indicate that 5.1 million older Americans – or 1-in-8 – suffer from Alzheimer’s, which makes it the sixth leading cause of death in the United States and the only cause of death among the top 10 in the United States that cannot be prevented, cured or even slowed. Estimated to effect 45 million people worldwide by 2020, dementia is currently a leading, major unmet medical need and a costly burden on public health. Seventy percent of these cases have been attributed to Alzheimer’s, a neurodegenerative pathology characterized by a progressive decline in cognitive functions.

“This collaborative partnership is a critical step in advancing discoveries of the role DYRK1A plays to developing therapeutics that could alter the course of Alzheimer’s disease,” said Dr. Dunckley.

Drs. Hulme and Dunckley will focus on providing a significant alternative to common approaches that focus on small molecules that inhibit the production of neurotoxic fragments of amyloid proteins and antibody immunization approaches targeting the build up of these fragments.

The joint effort will explore the decrease of DYRK1A activity in the brain with proprietary small-molecule inhibitors. This approach could lead to new therapeutic strategies to alleviate cognitive deficits associated with Alzheimer’s and Down syndrome.

BASIS_MESA_View_24

BASIS Selects Eastmark for Its Next East Valley School

The nationally renowned charter school BASIS has selected Eastmark for its next East Valley campus. Construction on BASIS Mesa at Eastmark commences in March 2013.  The new school is set to open fall 2013.

“BASIS is our first 5-12 educational partner and a perfect fit for this community.  Eastmark’s central location in the East Valley will give hundreds of children more opportunities to earn a world-class education, which is a tremendous value for kids, their families and our region’s future workforce,” said Dea McDonald, Senior Vice President of DMB Associates and General Manager of Eastmark.

“Every DMB community features education and lifelong learning among its Community Life pillars, which are empowered by partnerships that extend far beyond the classroom.  We’re delighted to bring to future residents and neighbors this charter school option in the early phase of Eastmark,” added McDonald.

The new BASIS Mesa at Eastmark will complement the East Valley BASIS programs.  Because of the strong interest by parents and students, the BASIS Board of Directors agreed there was enough demand to develop another school in the East Valley, explained Craig Barrett, retired Chairman/CEO of Intel Corporation and Chairman of the Board for BASIS Schools Inc.

“Our BASIS Chandler School has had a waiting list since we opened.  DMB brought us the opportunity to develop in their new community, in an early phase of the development, where we could be a true partner.  Its location, easy access to transportation and vision for the future made Eastmark the right choice for us.  We’re eager to grow another top performing school for the region,” Barrett said.

The BASIS Mesa at Eastmark will open with grades 5-10, adding grade 11 by 2014 and grade 12 by 2015. BASIS Mesa may also add K through 4thgrades in ensuing years.  The design and size of the new school will be similar to its Chandler and Phoenix campuses. The campus will be located adjacent to the Eastmark Great Park situated on approximately 4.5 acres. DMB is advancing the development and construction of Eastmark Parkway to meet the timelines of the opening of the charter school.

Families can sign up for the BASIS Mesa at Eastmark interest list at www.basislink.org.

The first phase of Eastmark’s residential development is in the Queen Creek School District.  The district does not have plans to build another campus in Eastmark in the immediate future.

Eastmark will host its grand opening on June 1, 2013 with seven builders offering homes in the first phase of residential development.

BASIS is the top performing school in Arizona with BASIS students ranked highest in Stanford 10 national test scores in both math and reading in 2012.
All BASIS schools are “A” rated by the Arizona Department of Education (“AZEd”).

Approximately 5,000 students attend BASIS schools with campuses in Tucson, Oro Valley, Scottsdale, Chandler, Flagstaff, Peoria and Washington, D.C.  BASIS is also opening new schools in Ahwatukee, San Antonio, and a new K-4 program in Tucson.

Biosphere 2, Photo: Flickr, C. G. P. Grey, www.CGPGrey.com

Things To Do In Arizona: Biosphere 2

Participate in something unique this summer that will not only educate, but help you get involved in your community — Biosphere 2.

Located north of Tuscon, Ariz., sitting at the base of the Santa Catalina Mountains, Biosphere 2 is a center of research, outreach, teaching and learning all about the Earth. But during your visit, you’ll also have the opportunity to become a member. By doing so, you’ll be able to get involved in the community and help out with various outreach programs, gaining hands-on experience that’s out of this world.

Biosphere 2 also offers tours, which include an introductory film, a historical overview, and a discussion of past and present research. Online, you’ll also find an interactive tour allowing you to explore the Biosphere 2 from an aerial view at your computer.

Always keeping its goal in mind, Biosphere 2 also offers an outreach and education program that provides community events and research experience for University of Arizona (UA) undergraduates. Community events include Science Saturday, Science Cafes and Citizen Science. Included with the cost of tour admission, Science Saturday events are designed to provide hands-on experience with science. Science Café, on the other hand, is a free event that allows UA scientists and the community to interact with one another at various venues in the area, such as Crushing Street, Saddlebrooke, Oro Valley, Green Valley, Sun City Vistoso, Gallagher Theater and Tumamoc Hill. And, lastly, Citizen Science is an opportunity to participate and help with science research and outreach efforts.

Whether you’re a lover of science, the Earth or interested in space, get involved at Biosphere 2. Plus, its surrounded by a natural desert preserve, and it was recently named one of the 50 must see “Wonders of the World” — so why wouldn’t you want to check it out?

For more information about Biosphere 2, please visit b2science.org.

Biosphere 2
32540 S. Biosphere Rd.
Tucson, AZ 85739
(520) 838-6200
b2science.org