tgen Archives

TGen: Dogs help advance new cancer treatments

Cancer research

A Science Translational Medicine review suggests integrating dogs with naturally occurring cancers into studies of new drug therapeutics could result in better treatments for our four-legged friends while helping inform therapeutic development for human cancers. The review, conducted by the Institute of Medicine (IOM) of the National Academy of Science, including faculty at the Translational Genomics Research Institute… Read More →

TGen finds protein that fuels invasive brain tumors

brain cancer

The Translational Genomics Research Institute (TGen) identified a protein called SGEF that promotes the survival of glioblastoma tumor cells and helps the cancer invade brain tissue. TGen researchers identified SGEF as a target for new brain cancer therapies in a study published Wednesday by Molecular Cancer Research, an American Association for Cancer Research journal. Glioblastoma multiforme, or… Read More →

TGen reports $174 million economic impact on Arizona

bioscience

Translational Genomics Research Institute (TGen) annual economic impact on Arizona has risen eight-fold over 8 years, reaching a total of $174 million annually, according to an independent financial report released Wednesday. Independent auditing firm Tripp Umbach of Pittsburgh’s report shows that TGen is responsible for $8.7 million is annual tax revenues to the state’s general… Read More →

Regents award TGen for outstanding service

bioscience

The Arizona Board of Regents presented the Translational Genomics Research Institute (TGen) with its 2015 Regents’ Award for Outstanding Service to Higher Education, recognizing the extensive research TGen has conducted in association with Northern Arizona University (NAU). The award was presented at a Board of Regents dinner Thursday at the University of Arizona. The award was established… Read More →

TGen finds drug that could help treat brain tumors

brain

In a significant breakthrough, the Translational Genomics Research Institute (TGen) has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer. In a study published today in the Journal of NeuroOncology, TGen researchers report that PPF works to limit the spread of glioblastoma multiforme, or GBM — the most common primary tumor of… Read More →

TGen leads Stand Up To Cancer Dream Team

123rf.com: Siarhei Lenets

The Phoenix-based Translational Genomics Research Institute (TGen) will lead an international Stand Up To Cancer (SU2C) Dream Team of top cancer researchers in a $12 million effort to double the survival of patients with pancreatic cancer, the fourth leading cause of cancer death in the U.S. Dr. Daniel D. Von Hoff — TGen Physician-in-Chief and… Read More →

TGen shows liquid biopsy improves cancer patient care

Strategic Economic Development Plan

A team of researchers, including scientists from the Translational Genomics Research Institute (TGen), has reported that analyzing circulating tumor DNA (ctDNA) can track how a patient’s cancer evolves and responds to treatment. In a study published today in Nature Communications, Dr. Muhammed Murtaza of TGen and Mayo Clinic, and colleagues, describe an extensive comparison between biopsy results… Read More →

TGen, HonorHealth study new therapy for pancreatic cancer

cancer

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute (TGen). “Results from our clinical trial research showed a patient survival rate of nearly… Read More →

FDA approves cancer drug tested by TGen

medical.research

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute (TGen). “Results from our clinical trial research showed a patient survival rate of nearly two… Read More →

TGen fundraiser helps children with rare disorders

concert

The 3rd annual “Mito What?” barbecue and concert, a fundraiser for TGen’s Center for Rare Childhood Disorders, is set for 11 a.m.-6 p.m. Oct. 24 at the Monastery in Mesa. The fundraising event for Phoenix-based non-profit TGen, the Translational Genomics Research Institute, is sponsored by Jayse’s Mito Rascals, Supporting Mitochondrial Disease Research. Mitochondrial diseases result from failures… Read More →

Protein found in malaria could help stop cancer

brain cancer

Researchers at the Translational Genomics Research Institute (TGen) joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer. Collaborators at the University of Copenhagen, while exploring why pregnant women are particularly susceptible to malaria, found that the mosquito-borne parasite that causes malaria also produces a protein that binds… Read More →

TGen test might predict breast cancer relapse

Phoenix Breast Cancer Awareness Events

Every woman successfully treated for breast cancer lives with the knowledge that it could come back. New research published in the journal Clinical Epigenetics may lead to a simple blood test to determine the risk of such recurrence, or the cancer invading other organs such as the lungs, bone or brain. Such a test would have profound… Read More →

$2.8 million study looks to detect and treat brain injuries

banner alzheimers foundation - brain research

Developing better treatments and an improved understanding of the biology behind brain injury from hemorrhagic strokes is the main goal of a three-year $2.8 million grant to the Translational Genomics Research Institute (TGen), Phoenix Children’s Hospital, and Barrow Neurological Institute. The funding comes from the National Institutes of Health’s National Center for Advancing Translational Sciences (NCATS)… Read More →

TGen, Riddell, ASU football study brain injuries

prevention trial - brain scan images

Riddell, the leader in football helmet technology and innovation, and the Translational Genomics Research Institute (TGen), a leader in cutting-edge genomic research, has began the third year of a study to advance concussion detection and treatment with the Pac-12’s Arizona State University and its Sun Devil football program. Researchers are working to identify biomarkers released from… Read More →