translational genomics research institute Archives

Regents award TGen for outstanding service

bioscience

The Arizona Board of Regents presented the Translational Genomics Research Institute (TGen) with its 2015 Regents’ Award for Outstanding Service to Higher Education, recognizing the extensive research TGen has conducted in association with Northern Arizona University (NAU). The award was presented at a Board of Regents dinner Thursday at the University of Arizona. The award was established… Read More →

TGen finds drug that could help treat brain tumors

brain

In a significant breakthrough, the Translational Genomics Research Institute (TGen) has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer. In a study published today in the Journal of NeuroOncology, TGen researchers report that PPF works to limit the spread of glioblastoma multiforme, or GBM — the most common primary tumor of… Read More →

TGen leads Stand Up To Cancer Dream Team

123rf.com: Siarhei Lenets

The Phoenix-based Translational Genomics Research Institute (TGen) will lead an international Stand Up To Cancer (SU2C) Dream Team of top cancer researchers in a $12 million effort to double the survival of patients with pancreatic cancer, the fourth leading cause of cancer death in the U.S. Dr. Daniel D. Von Hoff — TGen Physician-in-Chief and… Read More →

TGen, HonorHealth study new therapy for pancreatic cancer

cancer

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute (TGen). “Results from our clinical trial research showed a patient survival rate of nearly… Read More →

FDA approves cancer drug tested by TGen

medical.research

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute (TGen). “Results from our clinical trial research showed a patient survival rate of nearly two… Read More →

Protein found in malaria could help stop cancer

brain cancer

Researchers at the Translational Genomics Research Institute (TGen) joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer. Collaborators at the University of Copenhagen, while exploring why pregnant women are particularly susceptible to malaria, found that the mosquito-borne parasite that causes malaria also produces a protein that binds… Read More →

TGen teams with Barrow to find ALS biomarkers

123RF.com, Copyright: lightwise

The National Institutes of Health (NIH) has awarded a $687,087, one-year grant to Barrow Neurological Institute and the Translational Genomics Research Institute (TGen) to identify peptide, protein, and RNA biomarkers as indicators of Amyotrophic Lateral Sclerosis (ALS) progression. This degenerative disease, also known as Lou Gehrig’s disease, kills motor neurons — specialized nerve cells in the brain… Read More →

Magowitz Foundation gives $1 million for TGen

Cancer research

With a focus on supporting development of an early detection test for pancreatic cancer, the Seena Magowitz Foundation has presented $1 million to the Translational Genomics Research Institute (TGen). Dr. Daniel Von Hoff, a world leader in research and drug development, leads TGen’s pancreatic cancer research efforts. Through the Seena Magowitz Golf Classic, a well-known and… Read More →

TGen identifies genes linked to liver damage

Krauss Honored For Science

In a first-of-its-kind exploratory study, the Translational Genomics Research Institute (TGen) has identified a potential gene associated with the initiation of the most common cause of liver damage. Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver damage. In this study, published in the September edition of Translational Research, TGen scientists sequenced microRNAs (miRNAs) from… Read More →

TGen finds genes linked to pancreatic cancer survival

medical.research

A study by the Translational Genomics Research Institute (TGen) and other major research institutes, found a new set of genes that can indicate improved survival after surgery for patients with pancreatic cancer. The study also showed that detection of circulating tumor DNA in the blood could provide an early indication of tumor recurrence. In conjunction with the… Read More →

TGen finds gene giving children appearance of aging

Krauss Honored For Science

Researchers at the Translational Genomics Research Institute (TGen)have identified a genetic mutation associated with the appearance of premature aging and severe loss of body fat in children. TGen’s Center for Rare Childhood Disorders found that the appearance of premature aging, a neonatal form of Progeroid syndrome, in a 3-year-old girl was caused by a mutation… Read More →

Arizona Medical Association honors TGen’s Von Hoff

dan-von-hoff

Dr. Daniel D. Von Hoff, Distinguished Professor and Physician-In-Chief of the Translational Genomics Research Institute (TGen), will receive one of the top awards May 29 from the Arizona Medical Association (ArMA). Dr. Von Hoff will receive the 2015 Wallace A. Reed, M.D. Award, recognizing his accomplishments in advancing innovative cancer treatments, said Dr. Nathan Laufer,… Read More →

TGen, Phoenix Children’s Hospital look for new ways to store blood

stroke

The Translational Genomics Research Institute (TGen) and Phoenix Children’s Hospital are developing new economical methods of preserving, storing and transporting high-quality blood plasma proteins for use in diagnosing and treating disease. Under a $698,502 three-year grant from the National Institutes of Health, the Phoenix Children’s Hospital Biorepository and TGen’s Proteomics Division are using special filter… Read More →

TGen and Dell expand pediatric cancer fight

pharmaceuticals

Dell has announced its extended partnership with the Translational Genomics Research Institute (TGen) to help clinical researchers and doctors globally expand the reach and impact of the world’s first Food and Drug Administration (FDA)-approved precision medicine trial for pediatric cancer. The renewed commitment includes an additional $3 million Dell grant to support continued collaboration with… Read More →