Spotlighting the AZ Big 100 for 2026 shines a light on the 50 individuals and 50 companies shaping Arizona’s economic future. Selected by the Az Business editorial board in consultation with industry experts, this list of the 50 Arizona companies to watch in 2026 recognizes the visionaries, innovators and market-makers driving growth, investment and opportunity across the state. The AZ Big 100 captures who matters now—and who will define Arizona’s economy in the years ahead.


COMING TUESDAY: AZ Big 100: 50 Arizona business leaders to watch in 2026

COMING WEDNESDAY: AZ Big 100: 50 Arizona commercial real estate companies to watch in 2026

COMING THURSDAY: AZ Big 100: 50 Arizona commercial real estate leaders to watch in 2026


Achieve

Achieve has served more than 1.5 million members, resolved over $20 billion in debt, and given more than $10 billion in loans to help everyday people get on the path to a better financial future.

Align Technology

Align Technology’s global headquarters in Tempe anchors the orthodontic tech sector, creating jobs, boosting Arizona’s innovation profile, and strengthening its reputation as a hub for medical device development and high‑tech corporate investment.

Amkor Technology

Amkor’s expanding advanced semiconductor packaging campus in Peoria is a cornerstone of Arizona’s chip industry, driving multibillion‑dollar investment, thousands of jobs, and critical domestic semiconductor supply‑chain capacity.

Aprio Legal

Background: Aprio Legal is a full-service Alternative Business Structure Law Firm delivering integrated legal and advisory solutions to help clients grow with confidence. Formed by the combination of Radix Law and Aprio, Aprio Legal brings together attorneys, CPAs, tax professionals and business advisors to deliver a seamless, client-first experience. Licensed under Arizona’s ABS Program, Aprio Legal is headquartered in Scottsdale and serves business and individual clients.  

Goals for 2026: In 2026, Aprio Legal will continue expanding its presence across legal, accounting and wealth planning services as part of Aprio’s multidisciplinary approach to serving clients. The team plans to bring on additional attorneys and professionals to support its growing practice and strengthen coverage across litigation, employment, real estate, transactional, corporate and tax. A key focus will be deepening relationships with existing clients, providing seamless access to Aprio’s integrated platform. This approach allows entrepreneurs and business owners to make decisions with all advisors aligned, from legal and tax to wealth planning and strategic advisory, creating clarity, coordinated guidance and efficiency. Looking ahead, Aprio Legal aims to build on its model of holistic service, blending legal counsel with business insight and long-term planning to help entrepreneurs and business owners navigate growth, complexity and opportunity with confidence.

Learn more: legal.aprio.com

Arevon Energy

Headquartered in Scottsdale, Arevon Energy develops utility‑scale solar and energy‑storage projects nationwide, delivering clean power, community tax revenue, jobs, and renewable infrastructure while advancing grid reliability and energy independence.

Arizona State University

Arizona State University is a major economic engine, contributing billions to the state’s GDP, creating jobs, spurring startups and research commercialization, and supplying a skilled workforce that fuels regional innovation and growth.

ASM

ASM’s expansion in Scottsdale strengthens Arizona’s semiconductor ecosystem with advanced equipment manufacturing, significant capital investment and hundreds of local jobs supporting the state’s booming chip industry.

Assure Health Care Group of Arizona

Assure provides day treatment, employment services, community integration and life skills training that empower individuals with disabilities to achieve independence and confidence. 

Avnet

Global technology distributor headquartered in Phoenix, Avnet empowers local and regional tech innovation by connecting manufacturers and solutions providers with supply‑chain services, fueling Arizona’s electronics industry growth and reinforcing statewide tech leadership.

Banner Health

As one of Arizona’s largest health systems, Banner Health delivers comprehensive care through hospitals, clinics and research initiatives, improving health outcomes statewide and expanding medical access in urban and rural communities.

BeachFleischman

Arizona‑headquartered accounting and advisory firm BeachFleischman supports local businesses with tax, audit and consulting expertise, strengthening financial operations and fostering growth across diverse industries statewide.

Bell Bank

With multiple Arizona branches and community lending programs, Bell Bank supports homeownership, business banking and philanthropic initiatives while deepening its presence through local partnerships and economic engagement.


By integrating innovations with its portfolio of birth-tissue-derived wound coverings, BioLab Holdings is building a truly differentiated and comprehensive wound care ecosystem. (Photo provided by BioLab Holdings)

BioLab Holdings

Background: BioLab Holdings was born from a deep commitment to redefine what it means to care for patients; not only those suffering from chronic wounds, but individuals across the entire continuum of care. From the beginning, BioLab Holdings has embraced a patient-first philosophy, guided by a clear mission to elevate the standard of care in wound management and beyond. At its core, BioLab Holdings is built on a culture of humble leadership and people-first values. BioLab Holdings operates according to six guiding principles: performance, collaboration, innovation, integrity, care, and impact. These values are embedded in every partnership, product, and idea, fueling the company’s growth and reinforcing its vision. With a team dedicated to advancing care through both science and empathy, BioLab Holdings remains focused on creating meaningful, lasting change in healthcare.

Acts of innovation: “BioLab Holdings is most innovative in its ability to align best-of-breed wound care products, technologies and solutions from around the world into a unified platform that delivers value to patients, providers and payors. Central to this approach is advanced diagnostics, including our collaboration with Germany-based cureVision, which integrates AI-driven wound diagnostics with EMR systems to improve documentation accuracy and reduce administrative burden for providers. cureVision’s platform leverages machine learning and global treatment data to generate meaningful clinical insights that support better decision-making.” 

Goals for 2026 and beyond: “BioLab Holdings’ goal is to deliver meaningful value to its stakeholders—patients, providers, and payors (insurance)—by improving outcomes while reducing the overall cost of care. Guided by our continuum-of-care methodology, we are developing a portfolio of best-in-class wound care products and solutions designed to help patients heal better, faster, and more completely. Looking ahead to 2026 and beyond, BioLab is investing in the introduction of cutting-edge diagnostic and AI-driven solutions to the U.S. healthcare market. These innovations are intended to streamline patient care while delivering actionable insights and guidance to providers. In parallel, we are advancing new fish-collagen-based dressings and plasma-energy-driven technologies that together will form an unmatched and unprecedented wound care platform.”

Learn more: biolabholdings.com

City of Buckeye

One of America’s fastest‑growing cities, Buckeye fuels Arizona’s economy with residential expansion, logistics, manufacturing growth, and strategic location on key transportation corridors.

HonorHealth

HonorHealth is a major nonprofit healthcare network serving the Phoenix metro with hospitals, clinics and urgent care, providing comprehensive patient care, cancer treatment and community health services as one of Arizona’s largest health systems.

City of Goodyear

Goodyear fosters economic diversification through aerospace, manufacturing and healthcare growth, while attracting businesses, boosting employment and expanding mixed‑use developments that enhance community vibrancy.

Delta Dental of Arizona

Since 2010, DDAZ has invested $20 million-plus in initiatives that promote oral health education, disease prevention and food security. DDAZ also created a free directory of low-cost dental clinics across Arizona.

Desert Financial Credit Union

Since 2020, Desert Financial has grown from serving 320,000 Arizonans to 500,000, driving growth by giving back to members, community and our team. In 2026, Desert Financial will continue to amplify financial well-being for both members and employees. 

Eide Bailly

Eide Bailly is a Top 20 CPA firm, bringing practical expertise in tax, audit, advisory and technology. Its local team connects you to the full strength of a national firm to help you build a stronger business.

Enterprise Bank & Trust’s Arizona Regional President Brian Crisp. (Photo provided by Enterprise Bank & Trust)

Enterprise Bank & Trust

Background: Since its founding in 1988, Enterprise Bank & Trust has focused on guiding people to a lifetime of financial success. Enterprise empowers privately held businesses to succeed, help families secure their financial futures and invest to advance the quality of life in the communities it serves. Enterprise is headquartered in Clayton, Missouri, and operates more than 50 branch offices in Arizona, California, Florida, Kansas, Missouri, Nevada and New Mexico. Twelve of these branches are in Arizona. Enterprise Bank & Trust provides a range of business and personal banking services and a variety of specialized banking services. Enterprise is built on personal relationships and is dedicated to getting to know its clients and their businesses. What distinguishes Enterprise is its local decision-making and the structure to put the strength of an entire team behind each client. Enterprise also serves the state by investing in economic development initiatives and offering educational resources, like Enterprise University, the organization’s no-cost skill development program for professionals, to the wider business community. 

Learn more: enterprisebank.com/arizona

E Squared Marketing

E Squared combines over a decade of digital‑marketing expertise with an all‑women powerhouse team that’s nationally recognized for strategy, branding, ads, influencer outreach, web/video design, photography and social engagement. 

evolvedMD

Headquartered in Scottsdale, the company is redefining behavioral health by embedding services directly into primary care, a model that aligns with industry trends toward whole-person, value-based care.

Fortitude Family Office

Scottsdale‑based Fortitude delivers high‑touch wealth management, investment advisory and financial services to high‑net‑worth families, coordinating tax, estate, philanthropy and legacy planning while earning industry recognition for innovative client strategies and holistic financial solutions.

Grand Canyon Law Group

Background: Grand Canyon Law Group is a premier Arizona-based criminal defense firm dedicated to helping good people accused of a crime take control of their case and protect their future. With offices across the Phoenix metro area, and servicing the entire state of Arizona, the firm represents clients in DUI, domestic violence, drug offenses, weapons charges, assault, expungements and felony-level criminal matters. Founded on the core values of compassion, honesty and results, Grand Canyon Law Group blends aggressive legal strategy with a client-first approach. The firm is known for its high-touch service model, advanced operational systems, and commitment to transparency at every stage of representation. Backed by an experienced legal team, former prosecutors and forward-thinking leadership, the firm continues to set the standard for criminal defense in Arizona through innovation, community involvement and relentless advocacy for its clients.

Goals for 2026: “In 2026 and beyond, Grand Canyon Law Group is focused on scaling its impact through strategic expansion, advanced legal technology and elite talent development. Key initiatives include opening a new headquarters to support continued growth, expanding attorney and paralegal training academies, and implementing next-generation client communication and case management systems.”

Learn more: grandcanyon.law

GT Medical Tech

Tempe‑based GT Medical Technologies pioneers GammaTile® therapy, a groundbreaking surgically targeted radiation treatment for brain tumors, improving patient outcomes and earning bioscience awards while expanding adoption across top cancer centers nationwide.

HomeLight

Scottsdale‑based HomeLight is a real estate technology platform transforming how buyers and sellers connect with agents, using data‑driven matching and services to streamline transactions and elevate Arizona’s residential market experience.

Integro Bank

One of the fastest-growing banks in Arizona, Integro Bank outperformed many larger institutions in SBA 7a lending and is No. 1 in deposits growth for Arizona-based banks.

Lucid Motors

An electric vehicle manufacturer advancing Arizona’s EV ecosystem with its Casa Grande AMP‑1 factory, Lucid is creating thousands of jobs and over $100 million in economic impact while expanding EV production infrastructure in the state.

Insight Enterprises

Headquartered in Chandler, Insight is a Fortune 500 IT solutions provider, driving Arizona’s tech economy with cloud, hardware, software and digital transformation services while expanding local employment and innovation infrastructure.

Jennings Haug Keleher McLeod Waterfall

One of the oldest law firms in Arizona and founded in 1937, the firm has grown extensively in the past two years, adding offices in Albuquerque, Tucson and recently it expanded into Denver.

Kyl Center for Water Policy

The Kyl Center for Water Policy at ASU produces influential research and policy guidance on sustainable water management, shaping public dialogue and decision‑making on Arizona’s critical water resources and long‑term stewardship.

Lerner & Rowe

Over the past few years, the firm has achieved over $30 million in additional revenue, not by chasing volume or expanding for expansion’s sake, but by shifting the focus inward and committing to a “quality over quantity” mindset. 

LG Energy Solution Arizona

With a $5.5 billion facility being built in Queen Creek, LG Energy Solution leads the future eco-friendly energy industry by developing distinguished materials and next-generation batteries. 

Maricopa Corporate College

MCOR plays a crucial role in strengthening Arizona’s economy by partnering with businesses and industry to provide customized workforce training, skills development, and recruitment support that upskills employees, fills talent gaps and enhances productivity across key sectors.

National Bank of Arizona

Background: National Bank of Arizona (NBAZ) has served Arizona communities since 1984 with a mission to empower individuals and businesses to thrive. As Arizona’s premier local bank, National Bank of Arizona combines personalized service with innovative financial solutions to meet the unique needs of our state. With 56 branches statewide, NBAZ is deeply rooted in the communities it serves, supporting local businesses, investing in communities, and fostering economic growth. National Bank of Arizona’s commitment goes beyond banking; it’s about building lasting relationships and creating opportunities for Arizonans to succeed.

Goals for 2026: “Looking ahead, National Bank of Arizona is focused on strengthening its role as the bank for Arizona communities. Our initiatives include continually expanding digital banking capabilities while maintaining the personalized service our clients value. We will continue investing in Arizona’s business owners through tailored lending solutions and resources that fuel growth and innovation. Additionally, NBAZ is committed to community engagement by volunteering and investing in organizations that benefit Arizona. Our goal is simple: to help Arizona residents and businesses thrive today and for generations to come.”

Innovative acts: “Our digital banking platforms provide reliable, convenient access to financial tools, while our personalized consultative services help ensure clients receive solutions tailored to their goals. We’ve pioneered programs that support small businesses, offering flexible financing and resources that adapt to changing market conditions. Innovation at NBAZ isn’t just about technology, it’s about creating smarter, more responsive ways to serve Arizona communities.”

Learn more: nbarizona.com

Northern Arizona University

NAU fosters innovation through its dedicated office, NAU Innovations, for technology transfer, strong research in areas like health and ecosystems, key engineering programs and participation in statewide initiatives.

OneAZ Credit Union

This Phoenix‑based community‑focused financial institution has over 200,000 members and $3.4 billion in assets, driving local prosperity through tailored financial solutions and deep engagement in Arizona communities.

onsemi

This Scottsdale‑headquartered global semiconductor leader is producing power and sensing technologies for automotive, industrial, and consumer markets, supporting Arizona’s chip ecosystem and contributing to the state’s advanced manufacturing prominence.

Phillips Law Group

Background: For more than 30 years, Phillips Law Group has been one of Arizona’s most recognized personal injury firms, committed to protecting the rights of individuals and families across the state. With more than $2 billion recovered for clients and over 185,000 people helped, the firm has built its reputation on compassion, advocacy and results. From car accidents and wrongful death to trucking accidents and catastrophic injury cases, Phillips Law Group guides clients through some of life’s most challenging moments with clear communication and dedicated support. With offices statewide, a bilingual team and no upfront fees, the firm makes quality legal representation accessible to everyone. Phillips Law Group is also deeply rooted in community service through the Phillips Law Foundation, supporting nonprofits, public safety, veterans, youth programs and crisis response efforts. Driven by service and accountability, Phillips Law Group continues to stand up for injured Arizonans when they need it most.

Acts of innovation: “Phillips Law Group stands out for its innovation in client service and case management efficiency. While many firms react to cases, Phillips proactively builds systems that move them forward. The firm has one of the largest dedicated legal support teams in the state, intentionally structured to accelerate case progress, increase communication touchpoints and reduce client stress. Our approach integrates personalized service with streamlined processes so clients understand their case, feel supported and never wait for answers. Real-time updates, bilingual communication and accessible client support ensure every client receives attention and clarity from day one. Innovation at Phillips Law Group is rooted in compassion — technology, staffing and resources are designed around one goal: better experiences and faster results for injured Arizonans. By investing in people and processes rather than shortcuts, Phillips Law Group continues to lead with a client-first model that prioritizes action, accountability and meaningful outcomes.”

Learn more: phillipslaw.com

Procter & Gamble

This global consumer goods leader has invested $500 million in a new Coolidge manufacturing facility, creating more than 500 Arizona jobs and strengthening the state’s manufacturing base with fabric care product production.

Phoenix REALTORS

Phoenix REALTORS® is not just the Valley’s premier REALTOR association — it has forged a reputation for innovation and changed how brokers do business.

Resolution Copper

Resolution Copper’s proposed mega mine is projected to generate up to $61 billion in economic value over 60 years, create thousands of jobs, boost tax revenues and local supply‑chain spending, and support regional economic development.

Southwest Heritage Bank

Background: Southwest Heritage Bank is dedicated to the financial well-being of its entire community — from small to medium-sized businesses, to the families and individuals who call this region home. Southwest Heritage Bank provides comprehensive banking solutions, from essential online banking and bill pay to specialized services, all delivered by local experts. Whether you’re expanding operations, acquiring equipment or financing a new building, Southwest Heritage Bank’s experienced banking officers are dedicated to helping you achieve your financial goals. Southwest Heritage Bank is committed to consistently delivering responsive, tailored and expert banking services through local leadership.

Goals for 2026: “In 2026, Southwest Heritage Bank is focused on strengthening the financial future of the communities we proudly serve. Our goals center on delivering smarter, more personal banking experiences, whether that’s expanding access to digital tools that make everyday banking easier, offering flexible lending solutions for local businesses or investing in financial education that empowers our community business owners and families alike to plan confidently for tomorrow … As we continue to evolve, our values remain the same: to provide alert, assured and authentic guidance, responsive service, and innovative products that meet the real needs of the people who call our state home.”

Learn more: swhbank.com/

Sprouts Farmers Market

Arizona‑founded Sprouts Farmers Market drives economic activity with thousands of jobs, local produce sales, nutrition education programs, millions of pounds of food donated and significant community investment, reinforcing health and economic well‑being statewide. 

Taiwan Semiconductor Manufacturing Company (TSMC)

TSMC’s Phoenix “gigafab” semiconductor campus — one of the largest foreign investments in U.S. manufacturing — creates high‑wage jobs, strengthens supply chains, and anchors massive regional economic and industrial growth.

The Colibri Collective

The Colibri Collective, an award‑winning, Latina‑led full‑service marketing agency in Phoenix, elevates brands through creative, data‑driven campaigns for political, nonprofit, education and government clients, driving engagement, inclusion and community‑focused results.

UMB Bank

UMB supports Arizona communities with full‑service commercial, small business and personal banking, local lending and wealth management, while investing in regional economic growth through volunteerism, corporate giving and tailored financial solutions for individuals and businesses.

U.S. Bank

U.S. Bank is expanding its Arizona footprint with new Phoenix‑area branches, bolstering local banking access while supporting small businesses, community programs and financial inclusion through lending, volunteerism and targeted philanthropic initiatives shaping economic opportunity.

University of Arizona

The University of Arizona drives innovation and economic growth through leading research (nearly $1 billion annually), tech commercialization, startup support, and talent pipelines that strengthen Arizona’s workforce and entrepreneurial ecosystem.

University of Phoenix

Background: For 50 years, University of Phoenix has been a leader in flexible education, helping working adults advance their careers in a rapidly evolving workforce. The university offers career-focused degree and certificate programs tailored to fit busy lives. All associate, bachelor’s and master’s programs open for new enrollment are fully skills-mapped — enabling students to gain and showcase career-relevant skills in weeks, not years. Through its Career Services for Life® commitment, students and alumni receive lifetime access to career coaching, resources and tools at no added cost. The university’s workforce solutions team collaborates with employers to develop customized talent development programs aligned to in-demand skills. Additionally, research initiatives like the Career Optimism Index® and the Phoenix AI Research Group provide valuable insights on workforce trends and the responsible integration of AI in education.

Goals for 2026: Looking ahead, University of Phoenix is focused on delivering a more personalized learning experience. With connected, tech-enabled platforms built on robust data infrastructure, the university continues to integrate AI tools to enhance student learning, streamline processes and elevate support services — now expanding its focus on agentic, self-directed learning capabilities.

Learn more: phoenix.edu/

Wallace Plese + Dreher

Wallace, Plese + Dreher is a leading Arizona CPA and consulting firm providing accounting, tax, audit and advisory services that empower local businesses, support growth strategies and develop financial leadership across key industries statewide.

Waymo

Waymo’s autonomous ride‑hail service operates across more than 315 square miles of Metro Phoenix, expanding driverless mobility, advancing transportation innovation, increasing ride options, and testing autonomous freeway and delivery services that help position Arizona as a national AV hub.

Western Alliance Bank

Western Alliance Bank, headquartered in Phoenix, fuels Arizona’s economy by providing personalized business and community banking, supporting small‑business lending, affordable housing initiatives and financial literacy programs while driving local job creation and economic development.