Longevity trends, from Ozempic parties in Beverly Hills to AI-driven biohacking regimens in Silicon Valley, have often included a performative, “Insta-worthy” flair. Now a tiny molecule, invisible to the naked eye, is quietly capturing the wellness world’s imagination. Nicotinamide adenine dinucleotide, better known as NAD+, is a coenzyme found in every cell of the human body that plays a key role in producing energy and repairing DNA. As we age, NAD+ levels decline, and some researchers believe restoring those levels may help slow aging and improve overall health.

The result is a booming industry in NAD+ infusions, supplements, and nasal sprays, propelled by online buzz and celebrity endorsements. Hailey Bieber and Kendall Jenner have both reportedly turned to NAD+ therapy, crediting it with everything from increased energy to glowing skin.


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A Buzz Built on Biology — and Big Claims

While NAD+ plays a vital role in cellular health, much of the supporting research remains within laboratory settings. Recent preclinical studies indicate that increasing NAD+ levels might enhance memory, decrease inflammation, and potentially slow the progression of age-related diseases like Alzheimer’s and Parkinson’s. However, according to most experts, whether these results apply to humans is still uncertain.

That hasn’t stopped a cascade of over-the-counter NAD+ supplements, nasal sprays, and patches from hitting the market, often accompanied by bold marketing claims. Most are unregulated, unproven, and — according to experts — poorly absorbed when taken orally.

Kristin Anderson is the owner of North Peoria Prime IV Hydration and Wellness on Happy Valley Parkway.

Passionate Testimonials

Experience always outpaces the clinical process, and the personal accounts of progress are moving. A man who struggled with memory loss due to traumatic brain injury was brought to Prime IV by his daughter. Following a single NAD+ infusion, she reported that he could suddenly remember things like where he left his keys and what he’d eaten for breakfast, a simple feat he hadn’t done in weeks. He continues treatments and has seen steady improvement.

Another client, facing the early stages of Alzheimer’s, saw similar gains. According to his caregivers, mental clarity, recall, and independence improved after two sessions.

And in what may be the most striking anecdote, a woman diagnosed with chronic kidney failure in 2018 saw her eGFR — a measure of kidney function — climb from 26% to 48% over the course of a year’s worth of NAD+ infusions. Initially told she had seven years to live, she has now exceeded that timeline and calls the therapy a “lifesaver.”

But you don’t have to have an age-related disease to benefit from NAD+ therapy. Many people are getting lower-dose injections for general anti-aging and to improve energy. Melissa Salazar from Red Zen Tea said, “I’m 46 years old and NAD+ injections make me feel like a 20 year old again. I feel strong, full of energy and my workouts are easier. I feel like it’s given me my life back!”

But Is It Safe?

To date, no NAD+ therapy has been approved by the FDA, and the molecule remains classified as a supplement — meaning efficacy and safety claims are not held to the same regulatory standards as pharmaceuticals.

Side effects, though generally rare, include nausea, dizziness, and fatigue. Critics caution that when therapies are offered without medical oversight — especially in beauty spas or DIY kits — risks increase.

Clinics like Prime IV aim to counter that with transparency, insisting on supervised, lab-tested protocols and full ingredient disclosures. They also provide an anti-nausea medication for those who need it and an amino acid blend to aid in absorption.

Hype, Hope, or Both?

The popularity of NAD+ therapy reflects a broader cultural shift: from reactive healthcare to proactive self-optimization. In an era where biohacking is no longer fringe — and where aging itself is seen as a disease to be managed — interventions like NAD+ infusions are both aspirational and attainable.

And for many patients, the search for longevity is no longer confined to science fiction. It’s already in the IV bag. NAD+ therapy is offered at several Prime IV Hydration and Wellness throughout the Valley including Mesa, Peoria, Phoenix and Scottsdale. For more information visit primeivhydration.com today.


Author: Kristin Anderson is the owner of North Peoria Prime IV Hydration and Wellness on Happy Valley Parkway. As a leading clinic, Prime IV is dedicated to enhancing the lives of clients through IV hydration, weight loss plans, NAD+, and Bio- identical hormones for both men and women. Prime IV strives to help our clients look, feel and perform better. For more information visit primeivhydration.com today.