Daniel D. Von Hoff Archives

TGen begins Zebrafish pancreatic cancer studies


For more than a decade, a glassy striped fish smaller than a door key has proved an important model organism in scientific research. Named for the uniform horizontal stripes on the side of its body, the zebrafish is a tiny creature that packs a punch in terms of biological similarities with the human.Today, scientists at… Read More →

TGen fundraising event moves to Scottsdale


The 9th annual stepNout Run, Walk Dash, a major fundraising event for pancreatic cancer research at the Translational Genomics Research Institute (TGen), is moving to the Scottsdale Sports Complex. More than 1,000 participants have attended stepNout in each of the past few years, and even more are expected to attend this year’s morning-long event on… Read More →

TGen, SHC begin clinical trial for anti-tumor drug


The Virginia G. Piper Cancer Center at Scottsdale Healthcare and the Translational Genomics Research Institute (TGen) are studying the safety and effectiveness of a new drug, AG-120, for treatment of patients with solid tumors, especially those with brain tumors and gallbladder bile duct cancer. “AG-120 is designed specifically for those patients who carry the IDH1… Read More →

Pancreatic cancer drug successfully tested by TGen


A clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM-398, given in combination with 5-flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously-treated pancreatic cancer.… Read More →

SHC’s Von Hoff honored for cancer advances


In association with its 50th anniversary, the American Society of Clinical Oncology (ASCO) has named Daniel D. Von Hoff, M.D., FACP, one of ASCO’s 50 Oncology Luminaries, celebrating 50 doctors who over the past half-century have significantly advanced cancer care. Dr. Von Hoff is Chief Scientific Officer for Scottsdale Healthcare’s Virginia G. Piper Cancer Center… Read More →